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Design, synthesis and biological evaluation of PSMA/hepsin-targeted heterobivalent ligands

Cell surface biomarkers such as prostate-specific membrane antigen (PSMA) and hepsin have received considerable attention as targets for imaging prostate cancer (PCa) due to their high cell surface expression in such tumors and easy access for imaging probes. Novel amidine-containing indole analogs...

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Detalhes bibliográficos
Publicado no:Eur J Med Chem
Main Authors: Subedi, Milan, Minn, Il, Chen, Jianbo, Kim, YunHye, Ok, Kiwon, Jung, Yong Woo, Pomper, Martin G., Byun, Youngjoo
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4936276/
https://ncbi.nlm.nih.gov/pubmed/27128184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2016.04.033
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