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Enhanced Targeting with Heterobivalent Ligands

A novel approach to specifically target tumor cells for detection and treatment is the proposed use of hetero-multivalent ligands, which are designed to interact with, and non-covalently crosslink, multiple different cell surface receptors. Although enhanced binding has been shown for synthetic homo...

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Detalhes bibliográficos
Main Authors: Xu, Liping, Vagner, Josef, Josan, Jatinder, Lynch, Ronald M., Morse, David L., Baggett, Brenda, Han, Haiyong, Mash, Eugene A., Hruby, Victor J., Gillies, Robert J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3662534/
https://ncbi.nlm.nih.gov/pubmed/19671749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-08-1183
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