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A Low Molecular Weight PSMA-Based Fluorescent Imaging Agent for Cancer

We synthesized YC-27 3 to provide a fluorescent imaging probe for the prostate-specific membrane antigen (PSMA), a marker for hormone-independent prostate cancer and tumor neovasculature, with suitable pharmacokinetics for use in vivo. Immediate precursor trifluoroacetate salt of 2-(3-{5-[7-(5-amino...

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Bibliographic Details
Main Authors: Chen, Ying, Dhara, Surajit, Banerjee, Sangeeta Ray, Byun, Youngjoo, Pullambhatla, Mrudula, Mease, Ronnie C., Pomper, Martin G.
Format: Artigo
Language:Inglês
Published: 2009
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2787846/
https://ncbi.nlm.nih.gov/pubmed/19818734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2009.10.017
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