Titanium peroxide nanoparticles enhanced cytotoxic effects of X-ray irradiation against pancreatic cancer model through reactive oxygen species generation in vitro and in vivo

BACKGROUND: Biological applications of nanoparticles are rapidly increasing, which introduces new possibilities to improve the efficacy of radiotherapy. Here, we synthesized titanium peroxide nanoparticles (TiOxNPs) and investigated their efficacy as novel agents that can potently enhance the effect...

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Publicado en:Radiat Oncol
Autores principales: Nakayama, Masao, Sasaki, Ryohei, Ogino, Chiaki, Tanaka, Tsutomu, Morita, Kenta, Umetsu, Mitsuo, Ohara, Satoshi, Tan, Zhenquan, Nishimura, Yuya, Akasaka, Hiroaki, Sato, Kazuyoshi, Numako, Chiya, Takami, Seiichi, Kondo, Akihiko
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4936232/
https://ncbi.nlm.nih.gov/pubmed/27386977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13014-016-0666-y
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