Titanium peroxide nanoparticles enhanced cytotoxic effects of X-ray irradiation against pancreatic cancer model through reactive oxygen species generation in vitro and in vivo

BACKGROUND: Biological applications of nanoparticles are rapidly increasing, which introduces new possibilities to improve the efficacy of radiotherapy. Here, we synthesized titanium peroxide nanoparticles (TiOxNPs) and investigated their efficacy as novel agents that can potently enhance the effect...

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Enregistré dans:
Détails bibliographiques
Publié dans:Radiat Oncol
Auteurs principaux: Nakayama, Masao, Sasaki, Ryohei, Ogino, Chiaki, Tanaka, Tsutomu, Morita, Kenta, Umetsu, Mitsuo, Ohara, Satoshi, Tan, Zhenquan, Nishimura, Yuya, Akasaka, Hiroaki, Sato, Kazuyoshi, Numako, Chiya, Takami, Seiichi, Kondo, Akihiko
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2016
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4936232/
https://ncbi.nlm.nih.gov/pubmed/27386977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13014-016-0666-y
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