Titanium peroxide nanoparticles enhanced cytotoxic effects of X-ray irradiation against pancreatic cancer model through reactive oxygen species generation in vitro and in vivo

BACKGROUND: Biological applications of nanoparticles are rapidly increasing, which introduces new possibilities to improve the efficacy of radiotherapy. Here, we synthesized titanium peroxide nanoparticles (TiOxNPs) and investigated their efficacy as novel agents that can potently enhance the effect...

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Detalhes bibliográficos
Publicado no:Radiat Oncol
Main Authors: Nakayama, Masao, Sasaki, Ryohei, Ogino, Chiaki, Tanaka, Tsutomu, Morita, Kenta, Umetsu, Mitsuo, Ohara, Satoshi, Tan, Zhenquan, Nishimura, Yuya, Akasaka, Hiroaki, Sato, Kazuyoshi, Numako, Chiya, Takami, Seiichi, Kondo, Akihiko
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4936232/
https://ncbi.nlm.nih.gov/pubmed/27386977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13014-016-0666-y
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