Mutation of arginine residues to avoid non-specific cellular uptakes for hepatitis B virus core particles

BACKGROUND: The hepatitis B virus core (HBc) particle is known as a promising new carrier for the delivery of drugs and nucleic acids. However, since the arginine-rich domain that is located in the C-terminal region of the HBc monomer binds to the heparan sulphate proteoglycan on the cell surface du...

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Detalles Bibliográficos
Publicado en:J Nanobiotechnology
Autores principales: Bin Mohamed Suffian, Izzat Fahimuddin, Nishimura, Yuya, Morita, Kenta, Nakamura-Tsuruta, Sachiko, Al-Jamal, Khuloud T, Ishii, Jun, Ogino, Chiaki, Kondo, Akihiko
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2015
Materias:
Short Communication
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4334417/
https://ncbi.nlm.nih.gov/pubmed/25890025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12951-015-0074-8
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