A display of pH-sensitive fusogenic GALA peptide facilitates endosomal escape from a Bio-nanocapsule via an endocytic uptake pathway

BACKGROUND: An affibody-displaying bio-nanocapsule (Z(HER2)-BNC) with a hepatocyte specificity derived from hepatitis B virus (HBV) was converted into an affibody, Z(HER2), that recognizes HER2 receptors. This affibody was previously reported to be the result of the endocytosis-dependent specific up...

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Detalhes bibliográficos
Main Authors: Nishimura, Yuya, Takeda, Koichi, Ezawa, Ryosuke, Ishii, Jun, Ogino, Chiaki, Kondo, Akihiko
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Short Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4013831/
https://ncbi.nlm.nih.gov/pubmed/24690265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1477-3155-12-11
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