RhoA deficiency disrupts podocyte cytoskeleton and induces podocyte apoptosis by inhibiting YAP/dendrin signal

BACKGROUND: Podocyte apoptosis is a major mechanism that leads to proteinuria in many kidney diseases. However, the concert mechanisms that cause podocyte apoptosis in these kidney diseases are not fully understood. RhoA is one of Rho GTPases that has been well studied and plays a key role in regula...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:BMC Nephrol
Main Authors: Huang, Zongshun, Zhang, Li, Chen, Yuanhan, Zhang, Hong, Yu, Chunping, Zhou, Fangjian, Zhang, Zhiling, Jiang, Lijuan, Li, Ruizhao, Ma, Jianchao, Li, Zhuo, Lai, Yuxiong, Lin, Ting, Zhao, Xinchen, Zhang, Qianmei, Zhang, Bin, Ye, Zhiming, Liu, Shuangxin, Wang, Wenjian, Liang, Xinling, Liao, Ruyi, Shi, Wei
פורמט: Artigo
שפה:Inglês
יצא לאור: BioMed Central 2016
נושאים:
Research Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4936208/
https://ncbi.nlm.nih.gov/pubmed/27389190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12882-016-0287-6
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