RhoA deficiency disrupts podocyte cytoskeleton and induces podocyte apoptosis by inhibiting YAP/dendrin signal

BACKGROUND: Podocyte apoptosis is a major mechanism that leads to proteinuria in many kidney diseases. However, the concert mechanisms that cause podocyte apoptosis in these kidney diseases are not fully understood. RhoA is one of Rho GTPases that has been well studied and plays a key role in regula...

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Detalhes bibliográficos
Publicado no:BMC Nephrol
Main Authors: Huang, Zongshun, Zhang, Li, Chen, Yuanhan, Zhang, Hong, Yu, Chunping, Zhou, Fangjian, Zhang, Zhiling, Jiang, Lijuan, Li, Ruizhao, Ma, Jianchao, Li, Zhuo, Lai, Yuxiong, Lin, Ting, Zhao, Xinchen, Zhang, Qianmei, Zhang, Bin, Ye, Zhiming, Liu, Shuangxin, Wang, Wenjian, Liang, Xinling, Liao, Ruyi, Shi, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4936208/
https://ncbi.nlm.nih.gov/pubmed/27389190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12882-016-0287-6
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