NFAT2 inhibitor ameliorates diabetic nephropathy and podocyte injury in db/db mice

BACKGROUND AND PURPOSE: Podocyte injury plays a key role in the development of diabetic nephropathy (DN). We have recently shown that 11R-VIVIT, an inhibitor of cell-permeable nuclear factor of activated T-cells (NFAT), attenuates podocyte apoptosis induced by high glucose in vitro. However, it is n...

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Detalhes bibliográficos
Main Authors: Zhang, Li, Li, Ruizhao, Shi, Wei, Liang, Xinling, Liu, Shuangxin, Ye, Zhiming, Yu, Chunping, Chen, Yuanhan, Zhang, Bin, Wang, Wenjian, Lai, Yuxiong, Ma, Jianchao, Li, Zhuo, Tan, Xiaofan
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2013
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3834765/
https://ncbi.nlm.nih.gov/pubmed/23826864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12292
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