NFAT2 inhibitor ameliorates diabetic nephropathy and podocyte injury in db/db mice

BACKGROUND AND PURPOSE: Podocyte injury plays a key role in the development of diabetic nephropathy (DN). We have recently shown that 11R-VIVIT, an inhibitor of cell-permeable nuclear factor of activated T-cells (NFAT), attenuates podocyte apoptosis induced by high glucose in vitro. However, it is n...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Zhang, Li, Li, Ruizhao, Shi, Wei, Liang, Xinling, Liu, Shuangxin, Ye, Zhiming, Yu, Chunping, Chen, Yuanhan, Zhang, Bin, Wang, Wenjian, Lai, Yuxiong, Ma, Jianchao, Li, Zhuo, Tan, Xiaofan
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Blackwell Publishing Ltd 2013
Pynciau:
Research Papers
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3834765/
https://ncbi.nlm.nih.gov/pubmed/23826864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12292
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg