De Novo Guanine Biosynthesis but Not the Riboswitch-Regulated Purine Salvage Pathway Is Required for Staphylococcus aureus Infection In Vivo

De novo guanine biosynthesis is an evolutionarily conserved pathway that creates sufficient nucleotides to support DNA replication, transcription, and translation. Bacteria can also salvage nutrients from the environment to supplement the de novo pathway, but the relative importance of either pathwa...

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Pubblicato in:J Bacteriol
Autori principali: Kofoed, Eric M., Yan, Donghong, Katakam, Anand K., Reichelt, Mike, Lin, Baiwei, Kim, Janice, Park, Summer, Date, Shailesh V., Monk, Ian R., Xu, Min, Austin, Cary D., Maurer, Till, Tan, Man-Wah
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2016
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4936099/
https://ncbi.nlm.nih.gov/pubmed/27161118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00051-16
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