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Design and Antimicrobial Action of Purine Analogs that Bind Guanine Riboswitches

Riboswitches are structured RNA domains that can bind directly to specific ligands and regulate gene expression. These RNA elements are located most commonly within the noncoding regions of bacterial mRNAs, although representatives of one riboswitch class have been discovered in organisms from all t...

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Detalhes bibliográficos
Main Authors: Kim, Jane N., Blount, Kenneth F., Puskarz, Izabela, Lim, Jinsoo, Link, Kristian H., Breaker, Ronald R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4140397/
https://ncbi.nlm.nih.gov/pubmed/19739679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb900146k
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