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TRPC6 channel activation promotes neonatal glomerular mesangial cell apoptosis via calcineurin/NFAT and FasL/Fas signaling pathways

Glomerular mesangial cell (GMC) proliferation and death are involved in the pathogenesis of glomerular disorders. The mechanisms that control GMC survival are poorly understood, but may include signal transduction pathways that are modulated by changes in intracellular Ca(2+) ([Ca(2+)](i)) concentra...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Soni, Hitesh, Adebiyi, Adebowale
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4935859/
https://ncbi.nlm.nih.gov/pubmed/27383564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep29041
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