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TRPC6 channel activation promotes neonatal glomerular mesangial cell apoptosis via calcineurin/NFAT and FasL/Fas signaling pathways

Glomerular mesangial cell (GMC) proliferation and death are involved in the pathogenesis of glomerular disorders. The mechanisms that control GMC survival are poorly understood, but may include signal transduction pathways that are modulated by changes in intracellular Ca(2+) ([Ca(2+)](i)) concentra...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Soni, Hitesh, Adebiyi, Adebowale
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4935859/
https://ncbi.nlm.nih.gov/pubmed/27383564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep29041
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