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Urotensin II-induced store-operated Ca(2+) entry contributes to glomerular mesangial cell proliferation and extracellular matrix protein production under high glucose conditions

Glomerular mesangial cell (GMC) proliferation and matrix expansion are pathological hallmarks of a wide range of kidney diseases, including diabetic nephropathy. Although the circulating level of peptide hormone urotensin II (UII) and kidney tissue expression of UII and UII receptors (UTR) are incre...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Soni, Hitesh, Adebiyi, Adebowale
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5741753/
https://ncbi.nlm.nih.gov/pubmed/29273760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-18143-x
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