Monocyte polarization in children with falciparum malaria: relationship to nitric oxide insufficiency and disease severity

We earlier established that nitric oxide (NO) is protective against severe malaria and that arginine and NO levels are reduced in malaria patients. We now show that an M2-like blood monocyte phenotype is significantly associated with hypoargininemia, NO insufficiency, and disease severity in Tanzani...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Weinberg, J. Brice, Volkheimer, Alicia D., Rubach, Matthew P., Florence, Salvatore M., Mukemba, Jackson P., Kalingonji, Ayam R., Langelier, Charles, Chen, Youwei, Bush, Margaret, Yeo, Tsin W., Granger, Donald L., Anstey, Nicholas M., Mwaikambo, Esther D.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4935839/
https://ncbi.nlm.nih.gov/pubmed/27385484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep29151
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