Llwytho...
Evidence that cytochrome b(5) acts as a redox donor in CYP17A1 mediated androgen synthesis
Cytochrome P450 17A1 (CYP17A1) is an important drug target for castration resistant prostate cancer. It is a bi-functional enzyme, catalyzing production of glucocorticoid precursors by hydroxylation of pregnene- nucleus, and androgen biosynthesis by a second C-C lyase step, at the expense of glucoco...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | Biochem Biophys Res Commun |
|---|---|
| Prif Awduron: | , , , , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
2016
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4935565/ https://ncbi.nlm.nih.gov/pubmed/27297105 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2016.06.043 |
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