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Microsomal prostaglandin E synthase-1 protects against Fas-induced liver injury

Microsomal prostaglandin E synthase-1 (mPGES-1) is the terminal enzyme for the synthesis of prostaglandin E(2) (PGE(2)), a proproliferative and antiapoptotic lipid molecule important for tissue regeneration and injury repair. In this study, we developed transgenic (Tg) mice with targeted expression...

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Bibliographic Details
Published in:Am J Physiol Gastrointest Liver Physiol
Main Authors: Yao, Lu, Chen, Weina, Han, Chang, Wu, Tong
Format: Artigo
Language:Inglês
Published: American Physiological Society 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4935489/
https://ncbi.nlm.nih.gov/pubmed/27102561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00327.2015
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