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CYTOSOLIC PHOSPHOLIPASE A(2)α PROTECTS AGAINST FAS-BUT NOT LPS-INDUCED LIVER INJURY
BACKGROUND/AIMS: Cytosolic phospholipase A(2)α (cPLA(2)α) is a rate-limiting key enzyme controlling the release of arachidonic acid (AA) substrate for the synthesis of prostaglandins and leukotrienes. This study was designed to explore the role of hepatocyte cPLA(2)α in Fas-mediated liver injury, in...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3221788/ https://ncbi.nlm.nih.gov/pubmed/21703211 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2011.03.017 |
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