miR-223 Deficiency Protects against Fas-Induced Hepatocyte Apoptosis and Liver Injury through Targeting Insulin-Like Growth Factor 1 Receptor

The biological functions and molecular mechanisms of miR-223 action in liver cells and liver diseases remain unclear. We therefore determined the effect and mechanism of action of miR-233 in Fas-induced hepatocyte apoptosis and liver injury. Wild-type (WT) and miR-223 knockout (KO) mice were treated...

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Detalhes bibliográficos
Publicado no:Am J Pathol
Main Authors: Qadir, Ximena V., Chen, Weina, Han, Chang, Song, Kyoungsub, Zhang, Jinqiang, Wu, Tong
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2015
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4729243/
https://ncbi.nlm.nih.gov/pubmed/26598234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2015.08.020
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