Deletion of Mir155 Prevents Fas-Induced Liver Injury through Up-Regulation of Mcl-1

Fas-induced apoptosis is involved in diverse liver diseases. Herein, we investigated the effect of Mir155 deletion on Fas-induced liver injury. Wild-type (WT) mice and Mir155 knockout (KO) mice were i.p. administered with the anti-Fas antibody (Jo2) to determine animal survival and the extent of liv...

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Udgivet i:Am J Pathol
Main Authors: Chen, Weina, Han, Chang, Zhang, Jinqiang, Song, Kyoungsub, Wang, Ying, Wu, Tong
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Investigative Pathology 2015
Fag:
Regular Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4380848/
https://ncbi.nlm.nih.gov/pubmed/25794705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2014.12.020
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