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Parkin regulates mitophagy and mitochondrial function to protect against alcohol-induced liver injury and steatosis in mice
Alcoholic liver disease claims two million lives per year. We previously reported that autophagy protected against alcohol-induced liver injury and steatosis by removing damaged mitochondria. However, the mechanisms for removal of these mitochondria are unknown. Parkin is an evolutionarily conserved...
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| Опубликовано в: : | Am J Physiol Gastrointest Liver Physiol |
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| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Physiological Society
2015
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4556950/ https://ncbi.nlm.nih.gov/pubmed/26159696 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00108.2015 |
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