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Parkin regulates mitophagy and mitochondrial function to protect against alcohol-induced liver injury and steatosis in mice
Alcoholic liver disease claims two million lives per year. We previously reported that autophagy protected against alcohol-induced liver injury and steatosis by removing damaged mitochondria. However, the mechanisms for removal of these mitochondria are unknown. Parkin is an evolutionarily conserved...
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| 出版年: | Am J Physiol Gastrointest Liver Physiol |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Physiological Society
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4556950/ https://ncbi.nlm.nih.gov/pubmed/26159696 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00108.2015 |
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