Role of muscarinic-3 receptor antibody in systemic sclerosis: correlation with disease duration and effects of IVIG

Gastrointestinal dysmotility in systemic sclerosis (SSc) is associated with autoantibodies against muscarinic-3 receptor (M(3)-R). We investigated the temporal course of the site of action of these autoantibodies at the myenteric neurons (MN) vs. the smooth muscle (SM) M(3)-R in relation to disease...

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Detalhes bibliográficos
Publicado no:Am J Physiol Gastrointest Liver Physiol
Main Authors: Kumar, Sumit, Singh, Jagmohan, Kedika, Ramalinga, Mendoza, Fabian, Jimenez, Sergio A., Blomain, Erik S., DiMarino, Anthony J., Cohen, Sidney, Rattan, Satish
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2016
Assuntos:
Neurogastroenterology and Motility
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4935481/
https://ncbi.nlm.nih.gov/pubmed/27173508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00034.2016
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