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Effects of Scleroderma Antibodies and Pooled Human Immunoglobulin on Anal Sphincter and Colonic Smooth Muscle Function

BACKGROUND & AIMS: Patients with systemic sclerosis (SSc) have impairments in gastrointestinal smooth muscle function. The disorder has been associated with circulating antibodies to cholinergic muscarinic type-3 receptor (M(3)-R). We investigated whether it is possible to neutralize these antib...

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Detalhes bibliográficos
Main Authors: SINGH, JAGMOHAN, COHEN, SIDNEY, MEHENDIRATTA, VAIBHAV, MENDOZA, FABIAN, JIMENEZ, SERGIO A., DIMARINO, ANTHONY J., RATTAN, SATISH
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3480560/
https://ncbi.nlm.nih.gov/pubmed/22864255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2012.07.109
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