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The 1,2,3-triazole derivative KP-A021 suppresses osteoclast differentiation and function by inhibiting RANKL-mediated MEK-ERK signaling pathway

The triazole family of compounds has been implicated in modulating various biological processes such as inflammation, tumorigenesis, and infection. To our knowledge, this is the first study to demonstrate the effects of 1,2,3-triazole substituted biarylacrylonitrile compounds, including KP-A021, on...

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Detalhes bibliográficos
Publicado no:Exp Biol Med (Maywood)
Main Authors: Ihn, Hye Jung, Lee, Doohyun, Lee, Taeho, Shin, Hong-In, Bae, Yong Chul, Kim, Sang-Hyun, Park, Eui Kyun
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4935337/
https://ncbi.nlm.nih.gov/pubmed/25769316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1535370215576310
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