Inhibitory Effect of KP-A038 on Osteoclastogenesis and Inflammatory Bone Loss Is Associated With Downregulation of Blimp1

Excessive osteoclastic activity results in pathological bone resorptive diseases, such as osteoporosis, periodontitis, and rheumatoid arthritis. As imidazole-containing compounds possess extensive therapeutic potential for the management of diverse diseases, we synthesized a series of imidazole deri...

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Detalles Bibliográficos
Publicado en:Front Pharmacol
Main Authors: Ihn, Hye Jung, Lee, Taeho, Lee, Doohyun, Bae, Jong-Sup, Kim, Sang-Hyun, Jang, Il Ho, Bae, Yong Chul, Shin, Hong-In, Park, Eui Kyun
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2019
Assuntos:
Pharmacology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6467953/
https://ncbi.nlm.nih.gov/pubmed/31024321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00367
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