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Molecular and functional evaluation of a novel HIF inhibitor, benzopyranyl 1,2,3-triazole compound
Hypoxia occurs in a variety of pathological events, including the formation of solid tumors. Hypoxia-inducible factor (HIF)-1α is stabilized under hypoxic conditions and is a key molecule in tumor growth and angiogenesis. Seeking to develop novel cancer therapeutics, we investigated small molecules...
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| Publicado no: | Oncotarget |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Impact Journals LLC
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5352362/ https://ncbi.nlm.nih.gov/pubmed/27999195 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13955 |
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