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PDGF induces SphK1 expression via Egr-1 to promote pulmonary artery smooth muscle cell proliferation

Pulmonary arterial hypertension (PAH) is a progressive, life-threatening disease for which there is currently no curative treatment available. Pathologic changes in this disease involve remodeling of the pulmonary vasculature, including marked proliferation of pulmonary artery smooth muscle cells (P...

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Bibliografske podrobnosti
izdano v:Am J Physiol Cell Physiol
Main Authors: Sysol, Justin R., Natarajan, Viswanathan, Machado, Roberto F.
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4935200/
https://ncbi.nlm.nih.gov/pubmed/27099350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00059.2016
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