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PDGF induces SphK1 expression via Egr-1 to promote pulmonary artery smooth muscle cell proliferation

Pulmonary arterial hypertension (PAH) is a progressive, life-threatening disease for which there is currently no curative treatment available. Pathologic changes in this disease involve remodeling of the pulmonary vasculature, including marked proliferation of pulmonary artery smooth muscle cells (P...

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Detalhes bibliográficos
Publicado no:Am J Physiol Cell Physiol
Main Authors: Sysol, Justin R., Natarajan, Viswanathan, Machado, Roberto F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4935200/
https://ncbi.nlm.nih.gov/pubmed/27099350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00059.2016
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