Histone deacetylases positively regulate transcription through the elongation machinery

Transcription elongation regulates the expression of many genes, including oncogenes. Histone deacetylase (HDAC) inhibitors (HDACIs) block elongation, suggesting HDACs are involved in gene activation. To understand this, we analyzed nascent transcription and elongation factor binding genome-wide aft...

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Bibliographic Details
Published in:Cell Rep
Main Authors: Greer, Celeste B., Tanaka, Yoshiaki, Kim, Yoon Jung, Xie, Peng, Zhang, Michael Q., Park, In-Hyun, Kim, Tae Hoon
Format: Artigo
Language:Inglês
Published: 2015
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4934896/
https://ncbi.nlm.nih.gov/pubmed/26549458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.10.013
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