Histone deacetylases positively regulate transcription through the elongation machinery

Transcription elongation regulates the expression of many genes, including oncogenes. Histone deacetylase (HDAC) inhibitors (HDACIs) block elongation, suggesting HDACs are involved in gene activation. To understand this, we analyzed nascent transcription and elongation factor binding genome-wide aft...

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Publicat a:Cell Rep
Autors principals: Greer, Celeste B., Tanaka, Yoshiaki, Kim, Yoon Jung, Xie, Peng, Zhang, Michael Q., Park, In-Hyun, Kim, Tae Hoon
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4934896/
https://ncbi.nlm.nih.gov/pubmed/26549458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.10.013
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