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Histone deacetylases positively regulate transcription through the elongation machinery
Transcription elongation regulates the expression of many genes, including oncogenes. Histone deacetylase (HDAC) inhibitors (HDACIs) block elongation, suggesting HDACs are involved in gene activation. To understand this, we analyzed nascent transcription and elongation factor binding genome-wide aft...
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| Publié dans: | Cell Rep |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4934896/ https://ncbi.nlm.nih.gov/pubmed/26549458 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.10.013 |
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