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Histone deacetylases positively regulate transcription through the elongation machinery
Transcription elongation regulates the expression of many genes, including oncogenes. Histone deacetylase (HDAC) inhibitors (HDACIs) block elongation, suggesting HDACs are involved in gene activation. To understand this, we analyzed nascent transcription and elongation factor binding genome-wide aft...
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| Gepubliceerd in: | Cell Rep |
|---|---|
| Hoofdauteurs: | , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2015
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4934896/ https://ncbi.nlm.nih.gov/pubmed/26549458 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.10.013 |
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