Histone deacetylases positively regulate transcription through the elongation machinery

Transcription elongation regulates the expression of many genes, including oncogenes. Histone deacetylase (HDAC) inhibitors (HDACIs) block elongation, suggesting HDACs are involved in gene activation. To understand this, we analyzed nascent transcription and elongation factor binding genome-wide aft...

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Enregistré dans:
Détails bibliographiques
Publié dans:Cell Rep
Auteurs principaux: Greer, Celeste B., Tanaka, Yoshiaki, Kim, Yoon Jung, Xie, Peng, Zhang, Michael Q., Park, In-Hyun, Kim, Tae Hoon
Format: Artigo
Langue:Inglês
Publié: 2015
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4934896/
https://ncbi.nlm.nih.gov/pubmed/26549458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.10.013
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