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Asymmetric Pd-Catalyzed Alkene Carboamination Reactions for the Synthesis of 2-Aminoindane Derivatives

A new type of Pd-catalyzed alkene carboamination reaction that provides direct access to enantioenriched 2-aminoindanes from 2-allylphenyltriflate derivatives and aliphatic amines is described. A catalyst generated in situ from Pd(OAc)(2) and (S)-tert-ButylPHOX provides the functionalized carbocycle...

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Pubblicato in:J Am Chem Soc
Autori principali: White, Derick R., Hutt, Johnathon T., Wolfe, John P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4934887/
https://ncbi.nlm.nih.gov/pubmed/26313846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.5b07203
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