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Genetic Modification of Oncolytic Newcastle Disease Virus for Cancer Therapy
Clinical development of a mesogenic strain of Newcastle disease virus (NDV) as an oncolytic agent for cancer therapy has been hampered by its select agent status due to its pathogenicity in avian species. Using reverse genetics, we have generated a lead candidate oncolytic NDV based on the mesogenic...
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| Udgivet i: | J Virol |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4934751/ https://ncbi.nlm.nih.gov/pubmed/27009956 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00136-16 |
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