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Genetic Modification of Oncolytic Newcastle Disease Virus for Cancer Therapy

Clinical development of a mesogenic strain of Newcastle disease virus (NDV) as an oncolytic agent for cancer therapy has been hampered by its select agent status due to its pathogenicity in avian species. Using reverse genetics, we have generated a lead candidate oncolytic NDV based on the mesogenic...

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Detalhes bibliográficos
Publicado no:J Virol
Principais autores: Cheng, Xing, Wang, Weijia, Xu, Qi, Harper, James, Carroll, Danielle, Galinski, Mark S., Suzich, JoAnn, Jin, Hong
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4934751/
https://ncbi.nlm.nih.gov/pubmed/27009956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00136-16
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