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Genetic Analysis of Varicella-Zoster Virus ORF0 to ORF4 by Use of a Novel Luciferase Bacterial Artificial Chromosome System

To efficiently generate varicella-zoster virus (VZV) mutants, we inserted a bacterial artificial chromosome (BAC) vector in the pOka genome. We showed that the recombinant VZV (VZV(BAC)) strain was produced efficiently from the BAC DNA and behaved indistinguishably from wild-type virus. Moreover, VZ...

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Detalhes bibliográficos
Main Authors: Zhang, Zhen, Rowe, Jenny, Wang, Weijia, Sommer, Marvin, Arvin, Ann, Moffat, Jennifer, Zhu, Hua
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1951468/
https://ncbi.nlm.nih.gov/pubmed/17581997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02666-06
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