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Conformational Heterogeneity of Bax Helix 9 Dimer for Apoptotic Pore Formation
Helix α9 of Bax protein can dimerize in the mitochondrial outer membrane (MOM) and lead to apoptotic pores. However, it remains unclear how different conformations of the dimer contribute to the pore formation on the molecular level. Thus we have investigated various conformational states of the α9...
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| Publicat a: | Sci Rep |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4933972/ https://ncbi.nlm.nih.gov/pubmed/27381287 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep29502 |
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