The Role of a Nonribosomal Peptide Synthetase in l-Lysine Lactamization During Capuramycin Biosynthesis

Capuramycins are one of several known natural products that contain an l-Lys-derived l-α-amino-ε-caprolactam (l-ACL). The α-amino group of l-ACL in capuramycins is linked to an unsaturated hexuronic acid component through an amide bond that was previously shown to originate via an ATP-independent en...

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Detalhes bibliográficos
Publicado no:Chembiochem
Main Authors: Liu, Xiaodong, Jin, Yuanyuan, Cui, Zheng, Nonaka, Koichi, Baba, Satoshi, Funabashi, Masanori, Yang, Zhaoyong, Van Lanen, Steven G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4933962/
https://ncbi.nlm.nih.gov/pubmed/26840634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201500701
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