Telomere Visualization in Tissue Sections using Pyrrole–Imidazole Polyamide Probes

Pyrrole–Imidazole (PI) polyamides bind to specific DNA sequences in the minor groove with high affinity. Specific DNA labeling by PI polyamides does not require DNA denaturation with harsh treatments of heat and formamide and has the advantages of rapid and less disruptive processing. Previously, we...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Sasaki, Asuka, Ide, Satoru, Kawamoto, Yusuke, Bando, Toshikazu, Murata, Yukinori, Shimura, Mari, Yamada, Kazuhiko, Hirata, Akiyoshi, Nokihara, Kiyoshi, Hirata, Tatsumi, Sugiyama, Hiroshi, Maeshima, Kazuhiro
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4933941/
https://ncbi.nlm.nih.gov/pubmed/27380936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep29261
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