Sphingosine-1-phosphate Phosphatase 2 Regulates Pancreatic Islet β-Cell Endoplasmic Reticulum Stress and Proliferation

Sphingosine-1-phosphate (S1P) is a sphingolipid metabolite that regulates basic cell functions through metabolic and signaling pathways. Intracellular metabolism of S1P is controlled, in part, by two homologous S1P phosphatases (SPPases), 1 and 2, which are encoded by the Sgpp1 and Sgpp2 genes, resp...

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Dades bibliogràfiques
Publicat a:J Biol Chem
Autors principals: Taguchi, Yoshimitsu, Allende, Maria L., Mizukami, Hiroki, Cook, Emily K., Gavrilova, Oksana, Tuymetova, Galina, Clarke, Benjamin A., Chen, Weiping, Olivera, Ana, Proia, Richard L.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2016
Matèries:
Lipids
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4933255/
https://ncbi.nlm.nih.gov/pubmed/27059959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.728170
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