Transforming Growth Factor β1 (TGF-β1) Activates Hepcidin mRNA Expression in Hepatocytes

The hepatic hormone hepcidin is the master regulator of systemic iron homeostasis. Its expression level is adjusted to alterations in iron levels, inflammatory cues, and iron requirements for erythropoiesis. Bone morphogenetic protein 6 (BMP6) contributes to the iron-dependent control of hepcidin. I...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Biol Chem
Main Authors: Chen, Simeng, Feng, Teng, Vujić Spasić, Maja, Altamura, Sandro, Breitkopf-Heinlein, Katja, Altenöder, Jutta, Weiss, Thomas S., Dooley, Steven, Muckenthaler, Martina U.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2016
Teme:
Signal Transduction
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4933231/
https://ncbi.nlm.nih.gov/pubmed/27129231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.691543
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