Transforming Growth Factor β1 (TGF-β1) Activates Hepcidin mRNA Expression in Hepatocytes

The hepatic hormone hepcidin is the master regulator of systemic iron homeostasis. Its expression level is adjusted to alterations in iron levels, inflammatory cues, and iron requirements for erythropoiesis. Bone morphogenetic protein 6 (BMP6) contributes to the iron-dependent control of hepcidin. I...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Chen, Simeng, Feng, Teng, Vujić Spasić, Maja, Altamura, Sandro, Breitkopf-Heinlein, Katja, Altenöder, Jutta, Weiss, Thomas S., Dooley, Steven, Muckenthaler, Martina U.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4933231/
https://ncbi.nlm.nih.gov/pubmed/27129231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.691543
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