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Ethanol sensitizes hepatocytes for TGF-β-triggered apoptosis
Alcohol abuse is a global health problem causing a substantial fraction of chronic liver diseases. Abundant TGF-β—a potent pro-fibrogenic cytokine—leads to disease progression. Our aim was to elucidate the crosstalk of TGF-β and alcohol on hepatocytes. Primary murine hepatocytes were challenged with...
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| Publicado no: | Cell Death Dis |
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| Main Authors: | , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5833779/ https://ncbi.nlm.nih.gov/pubmed/29352207 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-017-0071-y |
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