Chargement en cours...
B-cell–independent sialylation of IgG
IgG carrying terminal α2,6-linked sialic acids added to conserved N-glycans within the Fc domain by the sialyltransferase ST6Gal1 accounts for the anti-inflammatory effects of large-dose i.v. Ig (IVIg) in autoimmunity. Here, B-cell–specific ablation of ST6Gal1 in mice revealed that IgG sialylation c...
Enregistré dans:
| Publié dans: | Proc Natl Acad Sci U S A |
|---|---|
| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2016
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4932940/ https://ncbi.nlm.nih.gov/pubmed/27303031 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1523968113 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|