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Sialylation Determines the Nephritogenicity of IgG3 Cryoglobulins
Monoclonal 6-19 IgG3 anti-IgG2a rheumatoid factor derived from lupus-prone MRL-Fas(lpr) mice can induce GN and cryoglobulinemia, but the features that confer nephritogenic potential are not completely understood. Asparagine-linked oligosaccharide chains of 6-19 IgG3 mAb are poorly galactosylated and...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Nephrology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3482736/ https://ncbi.nlm.nih.gov/pubmed/23024299 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2012050477 |
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