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O-Glycosylated IgA Rheumatoid Factor Induces IgA Deposits and Glomerulonephritis
Structural aberrations of O-linked glycans present in the IgA1 hinge region are associated with IgA nephropathy, but their contribution to its pathogenesis remains incompletely understood. In this study, mice implanted with hybridoma secreting 6-19 IgA anti-IgG2a rheumatoid factor, but not 46-42 IgA...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Nephrology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3294307/ https://ncbi.nlm.nih.gov/pubmed/22193386 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2011070701 |
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