T cell–independent B cell activation induces immunosuppressive sialylated IgG antibodies

Antigen-specific Abs are able to enhance or suppress immune responses depending on the receptors that they bind on immune cells. Recent studies have shown that pro- or antiinflammatory effector functions of IgG Abs are also regulated through their Fc N-linked glycosylation patterns. IgG Abs that are...

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Detalhes bibliográficos
Main Authors: Hess, Constanze, Winkler, André, Lorenz, Alexandra K., Holecska, Vivien, Blanchard, Véronique, Eiglmeier, Susanne, Schoen, Anna-Lena, Bitterling, Josephine, Stoehr, Alexander D., Petzold, Dominique, Schommartz, Tim, Mertes, Maria M.M., Schoen, Carolin T., Tiburzy, Ben, Herrmann, Anne, Köhl, Jörg, Manz, Rudolf A., Madaio, Michael P., Berger, Markus, Wardemann, Hedda, Ehlers, Marc
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754242/
https://ncbi.nlm.nih.gov/pubmed/23979161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI65938
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