T cell–independent B cell activation induces immunosuppressive sialylated IgG antibodies

Antigen-specific Abs are able to enhance or suppress immune responses depending on the receptors that they bind on immune cells. Recent studies have shown that pro- or antiinflammatory effector functions of IgG Abs are also regulated through their Fc N-linked glycosylation patterns. IgG Abs that are...

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Bibliografische gegevens
Hoofdauteurs: Hess, Constanze, Winkler, André, Lorenz, Alexandra K., Holecska, Vivien, Blanchard, Véronique, Eiglmeier, Susanne, Schoen, Anna-Lena, Bitterling, Josephine, Stoehr, Alexander D., Petzold, Dominique, Schommartz, Tim, Mertes, Maria M.M., Schoen, Carolin T., Tiburzy, Ben, Herrmann, Anne, Köhl, Jörg, Manz, Rudolf A., Madaio, Michael P., Berger, Markus, Wardemann, Hedda, Ehlers, Marc
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Clinical Investigation 2013
Onderwerpen:
Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754242/
https://ncbi.nlm.nih.gov/pubmed/23979161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI65938
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