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T cell–independent B cell activation induces immunosuppressive sialylated IgG antibodies

Antigen-specific Abs are able to enhance or suppress immune responses depending on the receptors that they bind on immune cells. Recent studies have shown that pro- or antiinflammatory effector functions of IgG Abs are also regulated through their Fc N-linked glycosylation patterns. IgG Abs that are...

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主要な著者: Hess, Constanze, Winkler, André, Lorenz, Alexandra K., Holecska, Vivien, Blanchard, Véronique, Eiglmeier, Susanne, Schoen, Anna-Lena, Bitterling, Josephine, Stoehr, Alexander D., Petzold, Dominique, Schommartz, Tim, Mertes, Maria M.M., Schoen, Carolin T., Tiburzy, Ben, Herrmann, Anne, Köhl, Jörg, Manz, Rudolf A., Madaio, Michael P., Berger, Markus, Wardemann, Hedda, Ehlers, Marc
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Clinical Investigation 2013
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オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3754242/
https://ncbi.nlm.nih.gov/pubmed/23979161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI65938
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