Development of self-reactive germinal center B cells and plasma cells in autoimmune FcγRIIB-deficient mice

Abnormalities in expression levels of the IgG inhibitory Fc gamma receptor IIB (FcγRIIB) are associated with the development of immunoglobulin (Ig) G serum autoantibodies and systemic autoimmunity in mice and humans. We used Ig gene cloning from single isolated B cells to examine the checkpoints tha...

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Main Authors: Tiller, Thomas, Kofer, Juliane, Kreschel, Cornelia, Busse, Christian E., Riebel, Stefan, Wickert, Susanne, Oden, Felix, Mertes, Maria M.M., Ehlers, Marc, Wardemann, Hedda
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2989760/
https://ncbi.nlm.nih.gov/pubmed/21078890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20100171
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