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Development of self-reactive germinal center B cells and plasma cells in autoimmune FcγRIIB-deficient mice
Abnormalities in expression levels of the IgG inhibitory Fc gamma receptor IIB (FcγRIIB) are associated with the development of immunoglobulin (Ig) G serum autoantibodies and systemic autoimmunity in mice and humans. We used Ig gene cloning from single isolated B cells to examine the checkpoints tha...
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| Autori principali: | , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The Rockefeller University Press
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2989760/ https://ncbi.nlm.nih.gov/pubmed/21078890 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20100171 |
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