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The Complex Association of FcγRIIb With Autoimmune Susceptibility

FcγRIIb is the only inhibitory Fc receptor and controls many aspects of immune and inflammatory responses. The observation 19 years ago that FcγRIIb(−/−) mice generated by gene targeting in 129 derived ES cells developed severe lupus like disease when backcrossed more than 7 generations into C57BL/6...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Verbeek, J. Sjef, Hirose, Sachiko, Nishimura, Hiroyuki
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6803437/
https://ncbi.nlm.nih.gov/pubmed/31681256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.02061
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